Ebola from emergence to epidemic: the virus and the disease, global preparedness and perspectives.
Identifieur interne : 001324 ( Main/Exploration ); précédent : 001323; suivant : 001325Ebola from emergence to epidemic: the virus and the disease, global preparedness and perspectives.
Auteurs : Kuldeep Dhama [Inde] ; Yashpal Singh Malik ; Satya Veer Singh Malik ; Raj Kumar SinghSource :
- Journal of infection in developing countries [ 1972-2680 ] ; 2015.
Descripteurs français
- KwdFr :
- Afrique de l'Ouest (épidémiologie), Animaux, Fièvre hémorragique à virus Ebola (), Fièvre hémorragique à virus Ebola (transmission), Fièvre hémorragique à virus Ebola (épidémiologie), Humains, Lutte contre l'infection (), Transmission de maladie infectieuse, Zoonoses (), Zoonoses (transmission), Zoonoses (épidémiologie), Épidémies.
- MESH :
English descriptors
- KwdEn :
- Africa, Western (epidemiology), Animals, Disease Transmission, Infectious, Epidemics, Hemorrhagic Fever, Ebola (epidemiology), Hemorrhagic Fever, Ebola (prevention & control), Hemorrhagic Fever, Ebola (transmission), Humans, Infection Control (methods), Zoonoses (epidemiology), Zoonoses (prevention & control), Zoonoses (transmission).
- MESH :
- geographic , epidemiology : Africa, Western.
- epidemiology : Hemorrhagic Fever, Ebola, Zoonoses.
- methods : Infection Control.
- prevention & control : Hemorrhagic Fever, Ebola, Zoonoses.
- transmission : Hemorrhagic Fever, Ebola, Zoonoses.
- Animals, Disease Transmission, Infectious, Epidemics, Humans.
Abstract
Humans constantly encounter threats from many infectious, zoonotic, and devastating pathogens. Outbreaks of severe acute respiratory syndrome (SARS), bird flu, and swine flu posing pandemic threats have compelled health agencies to follow global preparedness for combating the emerging deadly pathogens. The outbreak in West Africa of highly contagious Ebola viral disease (EVD) that started in Guinea in December 2013, assumed global proportions to become the largest outbreak of EVD and the most prominent international health concern. With fatality rates of nearly 50%-90%, it has claimed, as of 11 April 2015, 10,619 human lives out of a total of 25,626 cases reported worldwide. Ebola virus (EBOV), a member of Filoviridae family, is associated with severe, often lethal, hemorrhagic fever disease in humans and animals. The animal hosts, including non-human primates and reservoir hosts (fruit bats), play a significant role in transmission and maintenance of EBOV in nature. Although no approved vaccine for the prevention of EVD currently exists, disease control can be greatly enhanced by timely laboratory confirmation through blood tests using enzyme-linked immunosorbent assay (ELISA) and reverse transcription polymerase chain reaction (RT-PCR). Adherence to strict sanitary and hygienic measures, monitoring and surveillance of EBOV, as well as quarantine checks on international trade, transport, and visitors from affected countries are mandatory to prevent and control the spread of EVD. This review describes the salient properties of EBOV and the development of novel diagnostics, vaccines, and control strategies for this emerging disease of high public health concern and international emergency.
DOI: 10.3855/jidc.6197
PubMed: 25989163
Affiliations:
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Le document en format XML
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Malik</name></author><author><name sortKey="Malik, Satya Veer Singh" sort="Malik, Satya Veer Singh" uniqKey="Malik S" first="Satya Veer Singh" last="Malik">Satya Veer Singh Malik</name></author><author><name sortKey="Singh, Raj Kumar" sort="Singh, Raj Kumar" uniqKey="Singh R" first="Raj Kumar" last="Singh">Raj Kumar Singh</name></author></analytic><series><title level="j">Journal of infection in developing countries</title><idno type="eISSN">1972-2680</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Africa, Western (epidemiology)</term><term>Animals</term><term>Disease Transmission, Infectious</term><term>Epidemics</term><term>Hemorrhagic Fever, Ebola (epidemiology)</term><term>Hemorrhagic Fever, Ebola (prevention & control)</term><term>Hemorrhagic Fever, Ebola (transmission)</term><term>Humans</term><term>Infection Control (methods)</term><term>Zoonoses (epidemiology)</term><term>Zoonoses (prevention & control)</term><term>Zoonoses (transmission)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Afrique de l'Ouest (épidémiologie)</term><term>Animaux</term><term>Fièvre hémorragique à virus Ebola ()</term><term>Fièvre hémorragique à virus Ebola (transmission)</term><term>Fièvre hémorragique à virus Ebola (épidémiologie)</term><term>Humains</term><term>Lutte contre l'infection ()</term><term>Transmission de maladie infectieuse</term><term>Zoonoses ()</term><term>Zoonoses (transmission)</term><term>Zoonoses (épidémiologie)</term><term>Épidémies</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Africa, Western</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Hemorrhagic Fever, Ebola</term><term>Zoonoses</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Infection Control</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Hemorrhagic Fever, Ebola</term><term>Zoonoses</term></keywords><keywords scheme="MESH" qualifier="transmission" xml:lang="en"><term>Hemorrhagic Fever, Ebola</term><term>Zoonoses</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Afrique de l'Ouest</term><term>Fièvre hémorragique à virus Ebola</term><term>Zoonoses</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Disease Transmission, Infectious</term><term>Epidemics</term><term>Humans</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Fièvre hémorragique à virus Ebola</term><term>Humains</term><term>Lutte contre l'infection</term><term>Transmission de maladie infectieuse</term><term>Zoonoses</term><term>Épidémies</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Humans constantly encounter threats from many infectious, zoonotic, and devastating pathogens. Outbreaks of severe acute respiratory syndrome (SARS), bird flu, and swine flu posing pandemic threats have compelled health agencies to follow global preparedness for combating the emerging deadly pathogens. The outbreak in West Africa of highly contagious Ebola viral disease (EVD) that started in Guinea in December 2013, assumed global proportions to become the largest outbreak of EVD and the most prominent international health concern. With fatality rates of nearly 50%-90%, it has claimed, as of 11 April 2015, 10,619 human lives out of a total of 25,626 cases reported worldwide. Ebola virus (EBOV), a member of Filoviridae family, is associated with severe, often lethal, hemorrhagic fever disease in humans and animals. The animal hosts, including non-human primates and reservoir hosts (fruit bats), play a significant role in transmission and maintenance of EBOV in nature. Although no approved vaccine for the prevention of EVD currently exists, disease control can be greatly enhanced by timely laboratory confirmation through blood tests using enzyme-linked immunosorbent assay (ELISA) and reverse transcription polymerase chain reaction (RT-PCR). Adherence to strict sanitary and hygienic measures, monitoring and surveillance of EBOV, as well as quarantine checks on international trade, transport, and visitors from affected countries are mandatory to prevent and control the spread of EVD. This review describes the salient properties of EBOV and the development of novel diagnostics, vaccines, and control strategies for this emerging disease of high public health concern and international emergency. </div></front></TEI><affiliations><list><country><li>Inde</li></country></list><tree><noCountry><name sortKey="Malik, Satya Veer Singh" sort="Malik, Satya Veer Singh" uniqKey="Malik S" first="Satya Veer Singh" last="Malik">Satya Veer Singh Malik</name><name sortKey="Malik, Yashpal Singh" sort="Malik, Yashpal Singh" uniqKey="Malik Y" first="Yashpal Singh" last="Malik">Yashpal Singh Malik</name><name sortKey="Singh, Raj Kumar" sort="Singh, Raj Kumar" uniqKey="Singh R" first="Raj Kumar" last="Singh">Raj Kumar Singh</name></noCountry><country name="Inde"><noRegion><name sortKey="Dhama, Kuldeep" sort="Dhama, Kuldeep" uniqKey="Dhama K" first="Kuldeep" last="Dhama">Kuldeep Dhama</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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